The death toll from a car bomb claimed by Islamic State in the Iraqi capital's Sadr City district rose to 50, police and hospital sources said on Wednesday.
At least 60 others were wounded in the blast and many remained in critical condition, they added. The attack hit a crowded market during rush hour in a predominately Shi'ite Muslim area of eastern Baghdad.
The SUV packed with explosives went off near a beauty salon in a bustling market at rush hour in Sadr City. Most of the victims were women, the sources said.
Amaq news agency, which supports Islamic State, said a suicide bomber had targeted Shi'ite militia fighters.
The ultra-hardline Sunni jihadist group, which considers Shi'ites apostates, claimed a twin suicide bombing in Sadr City in February that killed 70 people.
The fight against Islamic State has exacerbated a long-running sectarian conflict in Iraq, mostly between the Shi'ite majority and the Sunni minority.
Sectarian violence also threatens to undermine efforts to dislodge the militant group from vast areas of the north and west of Iraq that they seized in 2014.