Iranian Foreign Minister Mohammad Javad Zarif on Sunday accused Twitter of closing accounts of "real" Iranians, while allowing anti-government ones backed by the United States.
In August, Facebook Inc, Twitter Inc and Alphabet Inc collectively removed hundreds of accounts tied to an alleged Iranian propaganda operation.
"Hello @Jack. Twitter has shuttered accounts of real Iranians, (including) TV presenters & students, for supposedly being part of an 'influence op'," Zarif said in a tweet, addressing Twitter CEO Jack Dorsey.
"How about looking at actual bots in (the Albanian capital of) Tirana used to prop up 'regime change' propaganda spewed out of (Washington) DC? #YouAreBots," Zarif said.
Twitter declined to comment when contacted by Reuters in the United States.
Iranian media have accused Israel, Saudi Arabia, and exiled opposition groups, including the Mujahideen Khalq which has some members based in Albania, of being behind social media campaigns calling for the overthrow of the Islamic government
Iranian Supreme Leader Ayatollah Ali Khamenei accused the United States and Israel this month of waging a media war to discourage Iranians, as the country faces economic hardship after the reimposition of US sanctions.