Iraq launched an air strike against an Islamic State target inside neighboring Syria on Thursday, the military said.
The F-16 fighter plane destroyed an area where members of the ultra-hardline Sunni group were operating, it said in a statement.
Islamic State, which once occupied a third of Iraq's territory, has been largely defeated in the country but still poses a threat along its border with Syria.
The Iraqi air force has carried out several air strikes against Islamic State in Syria since last year, with the approval of the Syrian government of President Bashar al-Assad and the US-led coalition fighting Islamic State.
Iraq has good relations with Iran and Russia, Assads main backers in the Syrian civil war, while also enjoying strong support from the US-led coalition.
Prime Minister Haider al-Abadi declared final victory over Islamic State in December but it still operates from pockets along the border with Syria and has continued to carry out ambushes, assassinations and bombings across Iraq.
Islamic State has resorted to guerrilla tactics since it abandoned its goal of holding territory and creating a self-sufficient caliphate that straddles Iraq and Syria.